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1

Cardioprotection by nicotinamide mononucleotide (NMN): Involvement of glycolysis and acidic pH

Nadtochiy, Sergiy M., Wang, Yves T., Nehrke, Keith, Munger, Josh, Brookes, Paul S.

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2018

Language:

english

File:

PDF, 7.77 MB

english, 2018

2

Secretion and cell volume regulation by salivary acinar cells from mice lacking expression of the Clcn3 Cl− channel gene

Jorge Arreola, Ted Begenisich, Keith Nehrke, Ha-Van Nguyen, Keerang Park, Linda Richardson, Baoli Yang, Brian C. Schutte, Fred S. Lamb, James E. Melvin

Journal:

The Journal of Physiology

Year:

2002

Language:

english

File:

PDF, 588 KB

english, 2002

3

Alternative splicing of N- and C-termini of a C. elegans ClC channel alters gating and sensitivity to external Cl− and H+

Jerod Denton, Keith Nehrke, Eric Rutledge, Rebecca Morrison, Kevin Strange

Journal:

The Journal of Physiology

Year:

2004

Language:

english

File:

PDF, 1.55 MB

english, 2004

4

Metabolic Acidosis Increases Intracellular Calcium in Bone Cells Through Activation of the Proton Receptor OGR1

Kevin K Frick, Nancy S Krieger, Keith Nehrke, David A Bushinsky

Journal:

Journal of Bone and Mineral Research

Year:

2009

Language:

english

File:

PDF, 1.06 MB

english, 2009

5

The inositol 1,4,5-trisphosphate receptor in C. elegans

Erik Allman, Baskaran Thyagarajan, Keith Nehrke

Journal:

Wiley Interdisciplinary Reviews: Membrane Transport and Signaling

Year:

2012

Language:

english

File:

PDF, 605 KB

english, 2012

6

Novel assay and regulation of the mitochondrial KATP channel

Andrew P. Wojtovich, Keith W. Nehrke, Paul S. Brookes

Journal:

Biochimica et Biophysica Acta (BBA) - Bioenergetics

Year:

2010

Language:

english

File:

PDF, 56 KB

english, 2010

7

Identification of a nuclear carbonic anhydrase in Caenorhabditis elegans

Teresa A. Sherman, Sharath C. Rongali, Tori A. Matthews, Jason Pfeiffer, Keith Nehrke

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Year:

2012

Language:

english

File:

PDF, 1.11 MB

english, 2012

8

Oscillatory Transepithelial H+ Flux Regulates a Rhythmic Behavior in C. elegans

Jason Pfeiffer, David Johnson, Keith Nehrke

Journal:

Current Biology

Year:

2008

Language:

english

File:

PDF, 671 KB

english, 2008

9

Ischemic preconditioning: The role of mitochondria and aging

Andrew P. Wojtovich, Sergiy M. Nadtochiy, Paul S. Brookes, Keith Nehrke

Journal:

Experimental Gerontology

Year:

2012

Language:

english

File:

PDF, 470 KB

english, 2012

10

Mitochondrial ATP-sensitive potassium channel activity and hypoxic preconditioning are independent of an inwardly rectifying potassium channel subunit in Caenorhabditis elegans

Andrew P. Wojtovich, Peter DiStefano, Teresa Sherman, Paul S. Brookes, Keith Nehrke

Journal:

Year:

2012

Language:

english

File:

PDF, 785 KB

english, 2012

11

Altered GABAergic function accompanies hippocampal degeneration in mice lacking ClC-3 voltage-gated chloride channels

Linda W. Dickerson, Daniel J. Bonthius, Brian C. Schutte, Baoli Yang, Thomas J. Barna, Melissa C. Bailey, Keith Nehrke, Roger A. Williamson, Fred S. Lamb

Journal:

Year:

2002

Language:

english

File:

PDF, 3.52 MB

english, 2002

12

A Quaternary Transcription Termination Complex: Reciprocal Stabilization by Rho Factor and NusG Protein

Keith W. Nehrke, Terry Platt

Journal:

Journal of Molecular Biology

Year:

1994

File:

PDF, 771 KB

1994

13

The C. elegans mitochondrial K+ATP channel: A potential target for preconditioning

Andrew P. Wojtovich, Lindsay S. Burwell, Teresa A. Sherman, Keith W. Nehrke, Paul S. Brookes

Journal:

Biochemical and Biophysical Research Communications

Year:

2008

Language:

english

File:

PDF, 356 KB

english, 2008

14

miR-786 Regulation of a Fatty-Acid Elongase Contributes to Rhythmic Calcium-Wave Initiation in C. elegans

Benedict J. Kemp, Erik Allman, Lois Immerman, Megan Mohnen, Maureen A. Peters, Keith Nehrke, Allison L. Abbott

Journal:

Current Biology

Year:

2012

Language:

english

File:

PDF, 907 KB

english, 2012

15

Carboxy Terminus Splice Variation Alters ClC Channel Gating and Extracellular Cysteine Reactivity

He, Liping, Denton, Jerod, Nehrke, Keith, Strange, Kevin

Journal:

Biophysical Journal

Year:

2006

Language:

english

File:

PDF, 571 KB

english, 2006

16

Bicarbonate modulates oxidative and functional damage in ischemia–reperfusion

Queliconi, Bruno B., Marazzi, Thire B.M., Vaz, Sandra M., Brookes, Paul S., Nehrke, Keith, Augusto, Ohara, Kowaltowski, Alicia J.

Journal:

Free Radical Biology and Medicine

Year:

2013

Language:

english

File:

PDF, 792 KB

english, 2013

17

Physiological consequences of complex II inhibition for aging, disease, and the mKATP channel

Wojtovich, Andrew P., Smith, C. Owen, Haynes, Cole M., Nehrke, Keith W., Brookes, Paul S.

Journal:

Biochimica et Biophysica Acta (BBA) - Bioenergetics

Year:

2013

Language:

english

File:

PDF, 774 KB

english, 2013

18

Expression of the CHOP-inducible carbonic anhydrase CAVI-b is required for BDNF-mediated protection from hypoxia

Matthews, Tori A., Abel, Allyssa, Demme, Chris, Sherman, Teresa, Pan, Pei-wen, Halterman, Marc W., Parkkila, Seppo, Nehrke, Keith

Journal:

Year:

2014

Language:

english

File:

PDF, 1.49 MB

english, 2014

19

Bicarbonate Modulates Oxidative and Functional Damage in Ischemia-Reperfusion

Barros Queliconi, Bruno, Marazzi, Thire B.M., Vaz, Sandra M., Brookes, Paul S., Nehrke, Keith W., Augusto, Ohara, Kowaltowski, Alicia J.

Journal:

Free Radical Biology and Medicine

Year:

2012

Language:

english

File:

PDF, 206 KB

english, 2012

20

The C. elegans intestinal Na+-H+ exchanger NHX-2 influences nutrient uptake and aging

Journal:

Gastroenterology

Year:

2003

Language:

english

File:

PDF, 182 KB

english, 2003

21

Genome-Wide Search and Identification of a Novel Gel-Forming Mucin MUC19/Muc19 in Glandular Tissues

Chen, Yin, Zhao, Yu Hua, Kalaslavadi, Tejas Baba, Hamati, Edward, Nehrke, Keith, Le, Anh Dao, Ann, David K., Wu, Reen

Journal:

American Journal of Respiratory Cell and Molecular Biology

Year:

2004

Language:

english

File:

PDF, 622 KB

english, 2004

22

Charge distribution of flanking amino acids inhibits O-glycosylation of several single-site acceptors in vivo

Nehrke, Keith, Ten Hagen, Kelly G., Hagen, Fred K., Tabak, Lawrence A.

Journal:

Year:

1997

Language:

english

File:

PDF, 1.87 MB

english, 1997

23

Overproduced rho factor from p39AS has lysine replacing glutamic acid at residue 155 in the linker region between its RNA and ATP binding domains

Nehrke, Keith W., Seifried, Steven E., Platt, Terry

Journal:

Nucleic Acids Research

Year:

1992

Language:

english

File:

PDF, 123 KB

english, 1992

24

Calcineurin Homologous Proteins Regulate the Membrane Localization and Activity of Sodium-Proton Exchangers in C. elegans

Allman, Erik, Wang, Qian, Walker, Rachel L, Austen, Molly, Peters, Maureen A., Nehrke, Keith

Journal:

AJP Cell Physiology

Year:

2015

Language:

english

File:

PDF, 2.50 MB

english, 2015

25

AC. elegansmodel of electronic cigarette use: Physiological effects of e-liquids in nematodes

Panitz, Daniel, Swamy, Harsha, Nehrke, Keith

Journal:

BMC Pharmacology and Toxicology

Year:

2015

Language:

english

File:

PDF, 1.56 MB

english, 2015

26

Cardiac Slo2.1 Is Required for Volatile Anesthetic Stimulation of K+ Transport and Anesthetic Preconditioning

Wojtovich, Andrew P., Smith, C. Owen, Urciuoli, William R., Wang, Yves T., Xia, Xiao-Ming, Brookes, Paul S., Nehrke, Keith

Journal:

Year:

2016

Language:

english

File:

PDF, 2.88 MB

english, 2016

27

Genetic hypercalciuric stone-forming rats

Bushinsky, David A, Frick, Kevin K, Nehrke, Keith

Journal:

Current Opinion in Nephrology & Hypertension

Year:

2006

Language:

english

File:

PDF, 3.44 MB

english, 2006

28

Acidic pH is a Metabolic Switch for 2-Hydroxyglutarate Generation and Signaling

Nadtochiy, Sergiy M., Schafer, Xenia, Fu, Dragony, Nehrke, Keith, Munger, Joshua, Brookes, Paul S.

Journal:

Journal of Biological Chemistry

Year:

2016

Language:

english

File:

PDF, 859 KB

english, 2016

29

Biosynthesis of a low-molecular-mass rat submandibular gland mucin glycoprotein in COS7 cells

NEHRKE, Keith, TABAK, Lawrence A.

Journal:

Biochemical Journal

Year:

1997

Language:

english

File:

PDF, 323 KB

english, 1997

30

Chromophore-Assisted Light Inactivation of Mitochondrial Electron Transport Chain Complex II in Caenorhabditis elegans

Wojtovich, Andrew P., Wei, Alicia Y., Sherman, Teresa A., Foster, Thomas H., Nehrke, Keith

Journal:

Scientific Reports

Year:

2016

Language:

english

File:

PDF, 1.51 MB

english, 2016

31

Active K + secretion through multiple K Ca -type channels and regulation by IK Ca channels in rat proximal colon

Joiner, William J., Basavappa, Srisaila, Vidyasagar, Sadasivan, Nehrke, Keith, Krishnan, Selvi, Binder, Henry J., Boulpaep, Emile L., Rajendran, Vazhaikkurichi M.

Journal:

American Journal of Physiology - Gastrointestinal and Liver Physiology

Year:

2003

Language:

english

File:

PDF, 432 KB

english, 2003

32

The Slo(w) path to identifying the mitochondrial channels responsible for ischemic protection

Smith, Charles Owen, Nehrke, Keith, Brookes, Paul S.

Journal:

Biochemical Journal

Year:

2017

Language:

english

File:

PDF, 1.43 MB

english, 2017

33

Potential mechanisms linking SIRT activity and hypoxic 2-hydroxyglutarate generation: no role for direct enzyme (de)acetylation

Nadtochiy, Sergiy M, Wang, Yves T, Zhang, Jimmy, Nehrke, Keith, Schafer, Xenia, Welle, Kevin, Ghaemmaghami, Sina, Munger, Joshua, Brookes, Paul S

Journal:

Biochemical Journal

Year:

2017

Language:

english

File:

PDF, 4.12 MB

english, 2017

34

An Anoxia-starvation Model for Ischemia/Reperfusion in C. elegans

Queliconi, Bruno B., Kowaltowski, Alicia J., Nehrke, Keith

Journal:

Journal of Visualized Experiments

Year:

2014

Language:

english

File:

PDF, 388 KB

english, 2014

35

The Mitophagy Receptor FUNDC-1 Contributes to Hypoxia-Reoxygenation Stress in C. elegans

Im, Yunki, Viteri, Stephanie, Brookes, Paul, Nehrke, Keith

Journal:

Free Radical Biology and Medicine

Year:

2017

Language:

english

File:

PDF, 91 KB

english, 2017

36

Cardiac metabolic effects of K Na 1.2 channel deletion and evidence for its mitochondrial localization

Smith, Charles O., Wang, Yves T., Nadtochiy, Sergiy M., Miller, James H., Jonas, Elizabeth A., Dirksen, Robert T., Nehrke, Keith, Brookes, Paul S.

Journal:

The FASEB Journal

Year:

2018

Language:

english

File:

PDF, 2.42 MB

english, 2018

37

Molecular identification of Ca 2+ -activated K + channels in parotid acinar cells

Nehrke, Keith, Quinn, Claire C., Begenisich, Ted

Journal:

AJP Cell Physiology

Year:

2003

Language:

english

File:

PDF, 431 KB

english, 2003

38

Acute inhibition of brain-specific Na + /H + exchanger isoform 5 by protein kinases A and C and cell shrinkage

Attaphitaya, Surat, Nehrke, Keith, Melvin, James E.

Journal:

American journal of physiology. Cell physiology

Year:

2001

Language:

english

File:

PDF, 375 KB

english, 2001

39

H(OH), H(OH), H(OH): a holiday perspective . Focus on “Mouse Slc4a11 expressed in Xenopus oocytes is an ideally selective H + /OH − conductance pathway that is stimulated by rises in intracellular and extracellular pH”

Journal:

American journal of physiology. Cell physiology

Year:

2016

Language:

english

File:

PDF, 154 KB

english, 2016

40

Targeted disruption of the Nhe1 gene fails to inhibit β 1 -adrenergic receptor-induced parotid gland hypertrophy

Melvin, James E., Nguyen, Ha-Van, Nehrke, Keith, Schreiner, Claire M., Ten Hagen, Kelly G., Scott, William

Journal:

American Journal of Physiology - Gastrointestinal and Liver Physiology

Year:

2001

Language:

english

File:

PDF, 303 KB

english, 2001

41

Fndc-1 contributes to paternal mitochondria elimination in C. elegans

Lim, Yunki, Rubio-Peña, Karinna, Sobraske, Peter J., Molina, Paola A., Brookes, Paul S., Galy, Vincent, Nehrke, Keith

Journal:

Developmental Biology

Year:

2019

Language:

english

File:

PDF, 2.26 MB

english, 2019

42

Cardioprotection by the mitochondrial unfolded protein response (UPR mt ) requires ATF5

Wang, Yves T, Lim, Yunki, McCall, Matthew Nicholson, Huang, Kai-Ting, Haynes, Cole M, Nehrke, Keith, Brookes, Paul S

Journal:

American journal of physiology. Heart and circulatory physiology

Year:

2019

Language:

english

File:

PDF, 6.40 MB

english, 2019

43

Fndc-1 contributes to paternal mitochondria elimination in C. elegans

Lim, Yunki, Rubio-Peña, Karinna, Sobraske, Peter J., Molina, Paola A., Brookes, Paul S., Galy, Vincent, Nehrke, Keith

Journal:

Developmental Biology

Year:

2019

File:

PDF, 2.26 MB

2019

44

Cardioprotection by the mitochondrial unfolded protein response (UPR mt ) requires ATF5

Wang, Yves T, Lim, Yunki, McCall, Matthew Nicholson, Huang, Kai-Ting, Haynes, Cole M, Nehrke, Keith, Brookes, Paul S

Journal:

American journal of physiology. Heart and circulatory physiology

Year:

2019

File:

PDF, 6.40 MB

2019

45

Semaphorin 3A potentiates the profibrotic effects of transforming growth factor-β1 in the cornea

Jeon, Kye-Im, Nehrke, Keith, Huxlin, Krystel R.

Journal:

Biochemical and Biophysical Research Communications

Year:

2019

Language:

english

File:

PDF, 1.25 MB

english, 2019

46

The Crosstalk Between Pathological Tau Phosphorylation and Mitochondrial Dysfunction as a Key to Understanding and Treating Alzheimerâs Disease

Guha, Sanjib, Johnson, Gail V. W., Nehrke, Keith

Journal:

Molecular Neurobiology

Year:

2020

File:

PDF, 1.11 MB

2020

47

Tauopathy-associated tau modifications selectively impact neurodegeneration and mitophagy in a novel C. elegans single-copy transgenic model

Guha, Sanjib, Fischer, Sarah, Johnson, Gail V. W., Nehrke, Keith

Journal:

Molecular Neurodegeneration

Year:

2020

File:

PDF, 1.79 MB

2020